Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma
- Creator: Pinkerton, James W. , Kim, Richard Y. , Baines, Katherine J. , Starkey, Malcolm R. , Kermani, Nazanin Z. , Guo, Yi-Ke , Robertson, Avril A. B. , O'Neill, Luke A. J. , Adcock, Ian M. , Cooper, Matthew A. , Gibson, Peter G. , Wood, Lisa G. , Brown, Alexandra C. , Hansbro, Philip M. , Horvat, Jay C. , Rae, Brittany E. , Donovan, Chantal , Mayall, Jemma R. , Carroll, Olivia R. , Ali, Md. Khadem , Scott, Hayley A. , Berthon, Bronwyn S.
- Resource Type: journal article
- Date: 2022
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease
- Creator: Ali, Md Khadem , Kim, Richard Y. , Borghuis, Theo , Karim, Rafia , Pinkerton, James W. , Aryal, Ritambhara , Heidari, Moones , Martin, Kristy L. , Burgess, Janette K. , Oliver, Brian G. , Trinder, Debbie , Johnstone, Daniel M. , Brown, Alexandra C. , Milward, Elizabeth A. , Hansbro, Philip M. , Horvat, Jay C. , Donovan, Chantal , Vanka, Kanth S. , Mayall, Jemma R. , Liu, Gang , Pillar, Amber L. , Jones-Freeman, Bernadette , Xenaki, Dikaia
- Resource Type: journal article
- Date: 2020
Crucial role for lung iron level and regulation in the pathogenesis and severity of asthma
- Creator: Ali, Md Khadem , Kim, Richard Y. , Donovan, Chantal , Pathinayake, Prabuddha S. , Carroll, Olivia R. , Trinder, Debbie , Tay, Hock L. , Badi, Yusef E. , Kermani, Nazanin Z. , Guo, Yi-Ke , Aryal, Ritambhara , Mumby, Sharon , Brown, Alexandra C. , Pavlidis, Stelios , Adcock, IM , Weaver, Jessica , Xenaki, D , Oliver, BG , Holliday, Elizabeth G. , Foster, Peter S. , Wark, Peter A. , Johnstone, DM , Milward, EA , Mayall, Jemma R. , Hansbro, Philip M. , Horvat, Jay C. , Karim, Rafia , Pinkerton, James W. , Liu, Gang , Martin, Kristy L. , Starkey, Malcolm R. , Pillar, Amber L.
- Resource Type: journal article
- Date: 2020
Human beta-defensin-2 suppresses key features of asthma in murine models of allergic airways disease
- Creator: Pinkerton, James W. , Kim, Richard Y. , Nordkild, Peter , Horvat, Jay C. , Jensen, Benjanim A. H. , Wehkamp, Jan , Hansbro, Philip M. , Koeninger, Louis , Armbruster, Nicole S. , Hansbro, Nicole G. , Brown, Alexandra C. , Jayaraman, Ranjith , Shen, Sijie , Malek, Nisar , Cooper, Matthew A.
- Resource Type: journal article
- Date: 2020
Inflammasomes in the lung
- Creator: Pinkerton, James W. , Kim, Richard Y. , Robertson, Avril A. B. , Hirota, Jeremy A. , Wood, Lisa G. , Knight, Darryl A. , Cooper, Matthew A. , O'Neill, Luke A. J. , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2017
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2
- Creator: Kim, Richard Y. , Horvat, Jay C. , Sunkara, Krishna P. , Nguyen, Thi Hiep , Jarnicki, Andrew G. , Keely, Simon , Mattes, Joerg , Adcock, Ian M. , Foster, Paul S. , Hansbro, Philip M. , Pinkerton, James W. , Starkey, Malcolm R. , Essilfie, Ama T. , Mayall, Jemma R. , Nair, Prema M. , Hansbro, Nicole G. , Jones, Bernadette , Haw, Tatt Jhong
- Resource Type: journal article
- Date: 2017
Role for NLRP3 inflammasome-mediated, IL-1ß-dependent responses in severe, steroid-resistant asthma
- Creator: Kim, Richard Y. , Pinkerton, James W. , Hirota, Jeremy A. , Wood, Lisa G. , Simpson, Jodie L. , Knight, Darryl A. , Wark, Peter A. , Gibson, Peter G. , O'Neill, Luke A. J. , Cooper, Matthew A. , Horvat, Jay C. , Hansbro, Philip M. , Essilfie, Ama T. , Robertson, Avril A. B. , Baines, Katherine J. , Brown, Alexandra C. , Mayall, Jemma R. , Ali, M. Khadem , Starkey, Malcolm R. , Hansbro, Nicole G.
- Resource Type: journal article
- Date: 2017
A short-term mouse model that reproduces the immunopathological features of rhinovirus-induced exacerbation of COPD
- Creator: Singanayagam, Aran , Glanville, Nicholas , Walton, Ross P. , Aniscenko, Julia , Pearson, Rebecca M. , Pinkerton, James W. , Horvat, Jay C. , Hansbro, Philip M. , Bartlett, Nathan W. , Johnston, Sebastian L.
- Resource Type: journal article
- Date: 2015
Inflammasomes in COPD and neutrophilic asthma
- Creator: Kim, Richard Y. , Pinkerton, James W. , Gibson, Peter G. , Cooper, Matthew A. , Horvat, Jay C. , Hansbro, Philip M.
- Resource Type: journal article
- Date: 2015
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
- Creator: Essilfie, Ama-Tawiah , Horvat, Jay C. , Hansbro, Philip M. , Kim, Richard Y. , Mayall, Jemma R. , Pinkerton, James W. , Beckett, Emma L. , Starkey, Malcolm R. , Simpson, Jodie L. , Foster, Paul S. , Gibson, Peter G.
- Resource Type: journal article
- Date: 2015